Anxiety and Depression Treatment
Medications for the Treatment of Anxiety and Depression
- SSRI (selective serotonin reuptake inhibitor)
ie) citalopram, escitalopram, fluoxetine, paroxetine, sertraline
- SNRI (serotonin-norepinephrine reuptake inhibitor)
ie) venlafaxine, duloxetine
- Tricyclic antidepressant
ie) amitriptyline, imipramine, nortriptyline
ie) alprazolam, clonazepam, diazepam, lorazepam
- MAOI’s (monoamine oxidase inhibitors)
- Beta blockers
Typical side effects of anxiety and depression medication
- Heart palpitations
- Tremor / Shakes
- Sexual dysfunction
- Weight gain
- Nausea and vomiting
- High blood pressure
CBT(cognitive behaviour therapy) highlights the thought processes aligned with the patient’s behaviour, and has been found useful for people from all walks of life and age., young to the elderly .
Medical Cannabis Treatment of Anxiety
Serotonin is an essential neurotransmitter involved in the regulation of mood, sleep, appetite and libido. In the central nervous system serotonin communicates with numerous receptors responsible for a variety of biological functions.
The precise mechanism by which the endocannabinoid system modulates anxiety and depression is not fully understood. CBD is postulated to act as an agonist to the 5HT1areceptor. Activation of the 5HT1a receptor is understood to modulate the release of serotonin in the brain. This hypothesis was confirmed in a study in which mice were pretreated with a 5HT1a antagonist, the antidepressant effects of CBD were absent. Further evidence of the role of 5HT1a is given by the observed similarities of CBD and isapirone (a 5HT1a partial agonist) in public speaking model.
Impairment of the hippocampal neurogenesis has been associated with the pathogenesis of anxiety disorders and depression. CBD is though to stimulate hippocampal neurogenesis a property absent in CB1 knockout mice. The researchers postulate that the mechanism is hence CB1 dependent, CBD is thought to reduce the efficiency of FAAH hence reduce anandamide reuptake; hence the CB1 receptor is activated.
Brazilian Researchers Investigate CBD and how it may alleviate symptoms of Anxiety In Humans
Recruiting 10 patients with diagnosed Social Anxiety Disorder, the research team began by doing an analysis of patient brains via functional neuroimaging. Taking a look at the amount of bloodflow within various sections of the brain, the researchers were able to note how this changed upon CBD oil treatment.
In the first session, half of the patients received an oral dose of 400 mg of cannabidiol (CBD). The other half of the patients received placebos. Reversing these roles in the 2nd session., this gave all patients the opportunity of being treated with CBD. The results indicated CBD reduced anxiety in patients with social anxiety disorder and they pointed out how this was related to its effects on activity in limbic and paralimbic brain areas. According to the results of the study, cannabidiol (CBD) was associated with a significant decrease in subjective anxiety. Cerebral bloodflow after CBD treatment indicated an anxiolitic (anti-anxiety) effect in the areas of the brain that manage emotions.
Anxiety Statistics in Australia
Depression Statistics in Australia
What is Anxiety and Depression?
Causes of Anxiety
- Changes in the brain
- Environmental stress
- Our family and upbringing
- Traumatic Event
Anxiety disorders start out in the brain. Scientists are considering the possibility that in some of those suffering from anxiety, there may be functional deficits in the brain circuitry that regulates fear and all the other emotions. Studies indicate that repeated exposure to stress has the propensity to alter nerve cells within the brain transmission that takes information from one part of the brain to another region for processing. It has been reported that those who suffer certain kinds of anxiety disorders have differences in the brain structure that control memories linked with strong emotions.
Symptoms of Anxiety
- Unrealistic fear or worry that causes a physical response
- Mental unrest
- Can’t shut off from the day causing sleep difficulty
- Racing thoughts
- Racing heart
- Clammy and cold hands/feet
- Inability to be calm
- Dry Mouth
- Quick tempered
- Feeling “crazy”
- On edge
- Chest Pain
- Stomach Pain
Types of Anxiety Disorders
- Generalised Anxiety Disorder
- Social Anxiety
- Panic Attacks
- Panic Disorder
- Obsessive Compulsive Disorder
- Post Traumatic Stress Disorder
Science Seeks to Unlock Marijuana’s Secrets
As the once-vilified drug becomes more accepted, researchers around the world are trying to understand how it works and how it might fight disease.
FORUM / BLOG:
Clinical Studies / References:
Medical Cannabis Clinic of Australia (MCCA) does not claim that any of its products are infallible or unfailing, nor does MCCA claim that all products will work in all cases of any specific condition. Inappropriate use can be harmful, use only as directed.